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KMID : 0356919760090020091
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Korean Journal of Anesthesiology
1976 Volume.9 No. 2 p.91 ~ p.95
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An Experimental Study of Positive End-Expiratong Pressure(PEEP) on Blood Gases during General Anesthesia
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金光宇/Kim, Kwang Woo
金庸樂/權武一/文賢洙/Kim, Yong Lack/Kwon, Moo Il/Moon, Hyun Soo
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Abstract
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Salient features of acute respiratory failure are redution of functional residual capacity, decreasedlung compliance and increased right to left shunt; and pneumonia, pulmonary congestion, atelectasis pulmonary dedma and fibrosis are revealed clinically.
PEEP is able to prevent alveolar collapse and avoid atelectatic change and increase functional residual capacity and lung compliance with increment of arterial oxygen content.
Decreased cardiac output and pulmonary parenchymal damages were noted during high PEEP.
Blood gases were observed with IL 213 Blood Gas Analyzer during 5㎝ H₂O of PEEP and general anesthesia in 10 healthy persons.
Following results were obtained:
1) 5㎝ H₂0 of PEEP increased PaO₂from 221 torr to 275 torr and PaCO₂from 38.8 torr to 42.1 torr.
2) 5㎝ H₂0 of PEEP increased PvO₂from 40 torr to 48 torr and PvCO₂from 44.1 torr to 49.3 torr.
3) 5㎝ H₂0 of PEEP increased mean arterial pressure but had no effect on heart rate.
4) 5㎝ H₂0 of PEEP increased C(a-v)DO₂from 5.306㏄/100ml to 5.433㏄/100ml.
5) It is noted that 5㎝ H₂0 of PEEP is safe in healthy persons.
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